TOKYO (AP) — Asian shares were trading mixed early Wednesday, as uncertainty remained about an initial deal to end the war in ...

In Southeast Missouri, nonprofits drive jobs, services and community life—discover how SECOP supports these charities, from ...

Deputies in Cape Girardeau County arrested a Charleston man after finding pounds of suspected meth and cocaine, a loaded ...

Serena Williams showed plenty of what made her a 23-time Grand Slam tennis champion in her first professional singles match ...

MoDOT to restrict Chester Bridge to one 10-foot lane July 1, 8 a.m.–4 p.m., for maintenance on Route 51 over the Mississippi ...

Murals and rehabbed homes are reshaping Bloomfield, where artist Katie Coleman’s downtown art and nonprofit Pioneer ...

Chester Bridge work to narrow Highway 51 to one lane, 10-foot width 8 a.m. to 4 p.m. Wednesday, July 1; weather permitting; ...

Heat warning in Southeast Missouri: highs in the mid-90s and heat indices of 106–112 degrees expected daily through at least ...

California brothers get 30- and 17-year federal sentences for running a meth, fentanyl and cocaine pipeline to southeast ...

Jersey Mike’s opens Wednesday on Campster Drive with a ribbon-cutting and kicks off ongoing fundraisers for Jackson-based dog ...

Two Cape Girardeau not-for-profits join forces to give unhoused neighbors safe winter shelter, reduce emergency costs and ...

Two Cole County lawsuits accuse Missouri AG Catherine Hanaway of unlawfully using prosecution and license threats to force ...