Deamidation of asparagine (Asn) is a spontaneous and non-enzymatic post-translational modification in proteins, playing a significant role in diseases related to aging such as Alzheimer’s and ...
Proteins in cells are highly flexible and often exist in multiple conformations, each with unique abilities to bind ligands. These conformations are regulated by the organism to control protein ...
Proteins in cells are highly flexible and often exist in multiple conformations, each with unique abilities to bind ligands. These conformations are regulated by the organism to control protein ...
A research group led by Prof. Wang Fangjun from the Dalian Institute of Chemical Physics (DICP) of the Chinese Academy of Sciences (CAS), in collaboration with Prof. Shun Feng from Southwest Jiaotong ...
How mutations impact protein stability and structure dynamics is crucial for understanding the molecular mechanism of the disease and the targeted drug design. However, probing the molecular details ...
Impurities in products may give rise to toxicities, but often represent only minor components. Thus the ability to detect these low abundant analytes in the presence of higher amounts of product is a ...
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