Microbiologists have visualized tiny islands in the cell membrane of baker's yeast. These membrane compartments appear to store transport proteins before use. The scientists observed that these ...

Researchers from the Göttingen Cluster of Excellence Multiscale Bioimaging (MBExC) have uncovered the 3D structure of the membrane proteins myoferlin and dysferlin using high-resolution cryo-electron ...

Cell membranes play a crucial role in maintaining the integrity and functionality of cells. However, the mechanisms by which they perform these roles are not yet fully understood. Scientists from the ...

Our remarkable ability to perform complex tasks—such as thinking, observing, and touch—stems from proteins, the tiny nanometer-sized molecules in the body. Despite decades of research, our ...

Collaboration between researchers at the University of Geneva, Institut de biologie structurale de Grenoble, and the University of Fribourg has shown how lipids and proteins in cell membranes react in ...

WEST LAFAYETTE, Ind. — Membrane proteins play an important role in many biological processes. Studies suggest they’re targeted by more than 50% of all modern medicinal drugs. Unfortunately for ...

Cryogenic optical microscopy uncovers multiple conformations of PIEZO1 in cell membranes, offering atomic-scale insights into how cells sense force. The team focused on PIEZO1, a mechanosensitive ion ...

Escherichia coli bacteria imaged by high-speed inline force mapping and fluorescence microscopy. Simultaneous topography and elastic modulus maps show a stiffening of the division site. Light and ...

The first study to elucidate the sequential dynamics of membrane cholesterol transport in erythrocytes infected with live Plasmodium falciparum parasites has been successfully concluded using the 3D ...

Fluorescent image of PIEZO1 in native cell membrane (left) and an artistic representation of its conformational states resolved with Ångström precision (right). Our remarkable ability to perform ...

Researchers have created an electron microscopy technique termed 'cryoAPEX' that accurately tracks membrane proteins in a well-preserved cell. Membrane proteins play an important role in many ...