The central role of 5,10-methylenetetrahydrofolate reductase (MTHFR) and methylenetetrahydrofolate dehydrogenase (MTHFD1) in folate metabolism renders polymorphisms in genes encoding these enzymes ...
A recent study reveals how the interaction of the epigenetic protein BRD4 with the metabolic enzyme MTHFD1 controls gene expression and cell proliferation. The results of the study have now been ...
While most enzymatic activity is conducted through chemical binding interactions between molecules, in some cases, the mere presence of an enzyme can affect intracellular functions. While exploring ...
This artistic rendering depicts a role for folate metabolism in BRD4-mediated transcription. The folate metabolic enzyme MTHFD1 is recruited to chromatin through physical interaction with BRD4.
Some results have been hidden because they may be inaccessible to you
Show inaccessible results