First-in-class metal-modulating epigenetic therapy targeting iron-dependent pathways with preclinical efficacy and a ...

Emerging biotechnology company aims to unlock targeting of disease-specific epigenetic protein interfaces to develop next-generation therapies for pediatric cancers SAN FRANCISCO, March 31, ...

The role of epigenetic mechanisms in cancer has gained interest in recent studies. The reversible nature of epigenetic changes on genomic DNA and histones holds promise for the development of ...

"Our project is innovative in its use of advanced epigenetic techniques combined with a novel preclinical model of PDAC survivorship," Dr. Arneson-Wissink said. "Together, these tools allow us to ...

It is well known that chronic inflammation can increase a person’s cancer risk, but the underlying mechanisms remain unknown. Now, a new study reveals, in a mouse model of colitis, gut tissues may ...

The world is full of microbes, and we don’t know anything about many of them. Lots of these microbes, which include bacteria, fungi, and viruses... | Genetics And Genomics ...

Chronic inflammation can raise a person's risk of cancer, and a new study reveals key details about how that might happen in ...

Methylation and cancer While these papers looked at the role of chromatin in the genetic expression of cancers, there are other laboratories looking at the role of methylation, another epigenetic ...

Chromatin is one of the earliest identified targets for cancer therapeutics. Drug development aimed at altering chromatin can be traced to the differentiating agents of the 1970s and their link to DNA ...

For patients with challenging cancers like lymphoma and sarcoma, these 3D images dramatically change the way doctors diagnose ...