Artificial DNA letters beyond A, T, G, C break a fundamental pairing rule to produce nanostructures with new shapes, far greater durability, and an unexpected ability to self-sort.

Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases. (Image: Wikimedia Commons, CC SA 3.0) The most common type of base pairing is the Watson-Crick base ...

For the first time, researchers have succeeded in developing an artificial DNA base pair that is based on a different chemical force than natural genetic material. While the common natural DNA ...

Engineers at the University of Pennsylvania and Rice University have refined a technology for editing individual genetic “base pairs” to a new level of precision, opening the door to safer, more ...